実績
2023-present ｜ 2025 ｜ 2024 ｜ 2023 ｜ 2005-2022 ｜
2025
原著論文
Kawade, K., Nozaki, M., Horiguchi, G., Mori, T., Yamaguchi, K., Okamoto, M., Tabeta, H., Shigenobu, S., Hirai, M.Y. and Tsukaya, H.(2025) Loss-of-functional mutation in ANGUSTIFOLIA3 causes leucine hypersensitivity and hypoxia response during Arabidopsis thaliana seedling growth.Metabolomics. 21:46. DOI:10.1007/s11306-025-02249-9. Yoshioka, H., Mary-Huard, T., Aubert, J., Toda, Y., Ohmori, Y., Yamasaki, Y., Tsujimoto, H., Takahashi, H., Nakazono, M., Takanashi, H., Fujiwara, T., Tsuda, M., Kaga, A., Inaba, J., Fuji, Y., Hirai, M.Y., Nose, Y., Kumaishi, K., Usui, E., Kobori, S., Sato, T., Narukawa, M., Ichihashi, Y. and Iwata, H. (2025) Integration of Proxy Intermediate Omics traits into a Nonlinear Two-Step model for accurate phenotypic prediction.bioRxiv 18:2. DOI:10.1101/2025.03.14.643213. Osuga, Y., Harada, K., Yamauchi, T., Kitaguchi, T., Hirai, M.Y., Matsumoto, M. and Tsuboi, T. (2025) Taurine promotes glucagon-like peptide-1 secretion in enteroendocrine L cells.FEBS Lett. DOI:10.1002/1873-3468.70014. Kim, J.-S., Sato, M., Kojima, M., Asrori, M.I., Uehara-Yamaguchi, Y., Takebayashi, Y., Do, T.N., Do, T.Y., Nguyen Thi, K.O., Sakakibara, H., Mochida, K., Ogita, S. and Hirai, M.Y.(2025) Multiomics-based assessment of the impact of airflow on diverse plant callus cultures.Sci Data. 12:197. DOI:10.1038/s41597-025-04518-7. Harada, K., Wada, E., Osuga, Y., Shimizu, K., Uenoyama, R., Hirai, M.Y., Maekawa, F., Miyazaki, M., Hayashi, Y.K., Nakamura, K. and Tsuboi, T. (2025) Intestinal butyric acid-mediated disruption of gut hormone secretion and lipid metabolism in vasopressin receptor-deficient mice.Mol Metab. 91:102072. DOI:10.1016/j.molmet.2024.102072. Zhao, X., Su, H., Kong, X., Hirai, M.Y., Yan, X., Li, R. and Li, J. (2025) Overexpression of BoSULTR1;1/BoSULTR1;2 promotes glucosinolate accumulation and enhances stress tolerance in broccoli. Sci. Hortic. 339. DOI:10.1016/j.scienta.2024.113883. Okamoto, T., Hotta, Y., Shinjo, R., Masuda, Y., Nishihara, A., Sasaki, R., Hirai, M.Y., Nishiwaki, R., Miyado, S., Sugiura, D. and Kondo, M. (2025) Unelongated Stems are an Active Nitrogen-Fixing Site in Rice Stems Supported by Both Sugar and Methane Under Low Nitrogen Conditions. Rice 18:2. DOI:10.1186/s12284-025-00757-9. Harada, K., Wada, E., Osuga, Y., Shimizu, K., Uenoyama, R., Hirai, M.Y., Maekawa, F., Miyazaki, M., Hayashi, Y.K., Nakamura, K. and Tsuboi, T. (2025) Intestinal butyric acid-mediated disruption of gut hormone secretion and lipid metabolism in vasopressin receptor-deficient mice.Mol Metab. 91:102072. DOI:10.1016/j.molmet.2024.102072.その他の発行物
バイオサイエンスとインダストリー83巻1号「根の形態を制御可能な機能性アミノ酸：2-アミノピメリン酸」
多部田弘光、平井優美
2024
巻頭言（エディトリアル）
Mitsuda, N., Seki, H., Shoji, T., and Hirai, M.Y. (2024) Preface to the special issue “Synthetic Biology and Bioproduction in Plants”, Plant Biotechnology 41: 169-171.
Li-Beisson, Y., Hirai, M.Y., Nakamura, Y. (2024) Plant metabolomics. Journal of Experimental Botany 75: 1651–1653.
原著論文
Dang, T., Fuji, Y., Kumaishi, K., Usui, E., Kobori, S., Sato, T., Toda, Y., Sakurai, K., Yamasaki, Y., Tsujimoto, H., Hirai, M.Y., Ichihashi, Y. and Iwata, H. (2024) I-SVVS: Integrative stochastic variational variable selection to explore joint patterns of multi-omics microbiome data bioRxiv. DOI: 10.1101/2023.08.18.553796 Uchida, K., Fuji, Y., Tabeta, H., Akashi, T. and Hirai, M.Y. (2024) Omics-based Identification of the Broader Effects of 2-hydroxyisoflavanone Synthase Gene Editing on a Gene Regulatory Network Beyond Isoflavonoid Loss in Soybean Hairy Roots Plant Cell Physiol.. DOI: 10.1093/pcp/pcae151 Okada, M., Barras, C., Toda, Y., Hamazaki, K., Ohmori, Y., Yamasaki, Y., Takahashi, H., Takanashi, H., Tsuda, M. and Hirai, M.Y. , et al.(2024) High-Throughput Phenotyping of Soybean Biomass: Conventional Trait Estimation and Novel Latent Feature Extraction Using UAV Remote Sensing and Deep Learning Models, Plant Phenomics. 2024;6:0244, DOI: 10.34133/plantphenomics.0244. Fuji, Y., Matsufuji, H. and Hirai, M.Y. (2024) Distribution, biosynthesis, and synthetic biology of phenylethanoid glycosides in the order Lamiales, Plant Biotechnology. 41: 231-241, DOI: 10.5511/plantbiotechnology.24.0720a. Kim, J.-S., Sato, M., Kojima, M., Asrori,M.I., Uehara-Yamaguchi, Y., Takebayashi, Y., Do, T.N., Do, T.Y., Nguyen, K.-O.T., Sakakibara, H., Mochida, K., Ogita, S. and Hirai, M.Y. (2024) Multi-omics signatures of diverse plant callus cultures, Plant Biotechnology. 41: 309-314, DOI: 10.5511/plantbiotechnology.24.0719a. Ishii, K., Kazama, Y., Hirano, T., Fawcett, J.A., Sato, M., Hirai, M.Y., Sakai, F., Shirakawa, Y., Ohbu, S. and Abe, T.(2024) Genomic view of heavy-ion-induced deletions associated with distribution of essential genes in Arabidopsis thaliana. Front Plant Sci.. 15:1352564. DOI: 10.3389/fpls.2024.1352564. Tabeta, H. and Hirai, M.Y.(2024) L-2-Aminopimelic acid acts as an auxin mimic to induce lateral root formation across diverse plant species. FEBS Letters. DOI:10.1002/1873-3468.14908 Nguyen, P.N., Do, T.Y., Do, T.N., Gontier, E., Nguyen, H.T.L., Thi, V.A.L., Mai, N.T.P., Sato, M., Hirai, M.Y. and Nguyen, K.-O.T.(2024) Widely targeted metabolomics reveals the species-specific, matureness-specific and post-harvest-specific discriminations in the chemical profiles of Vietnamese endemic golden camellias. Int J Food Sci Technol. DOI:10.1111/ijfs.17071 Uzaki, M., Mori, T., Sato, M., Wakazaki, M., Takeda-Kamiya, N., Yamamoto, K., Murakami, A., Guerrero, D.A.S., Shichijo, C., Ohnishi, M., Ishizaki, K., Fukaki, H., O'Connor, S.E., Toyooka, K., Mimura, T. and Hirai, M.Y.(2024) Integration of cell differentiation and initiation of monoterpenoid indole alkaloid metabolism in seed germination of Catharanthus roseus. New Phytol. DOI:10.1111/nph.19662 Miyaji, S., Ito, T., Kitaiwa, T., Nishizono, K., Agake, S.-I., Harata, H., Aoyama, H., Umahashi, M., Sato, M., Inaba, J., Fushinobu, S., Yokoyama, T., Murayama-Nakashita, A., Hirai, M.Y. and Ohkama-Ohtsu, N.(2024) N2-Acetylornithine deacetylase functions as a Cys-Gly dipeptidase in the cytosolic glutathione degradation pathway in Arabidopsis thaliana Plant J.. DOI:10.1111/tpj.16700. Wang, M., Tabeta, H., Ohtaka, K., Kuwahara, A., Nishihama, R., Ishikawa, T., Toyooka, K., Sato, M., Wakazaki, M., Akashi, H., Tsugawa, H., Shoji, T., Okazaki, Y., Yoshida, K., Sato, R., Ferjani, A., Kohchi, T., Hirai, M.Y. (2024) The phosphorylated pathway of serine biosynthesis affects sperm, embryo, and sporophyte development, and metabolism in Marchantia polymorpha. Commun Biol. DOI:10.1038/s42003-023-05746-6.2023
巻頭言（エディトリアル）
Hirai, M.Y., Mizutani, M. and Nakamura, Y.(2023) Revisiting Plant Metabolite Functions. Plant Cell Physiol.,DOI:10.1093/pcp/pcad155.原著論文
Horikoshi, M., Harada, K., Tsuno, S., Kitaguchi, T., Hirai, M.Y., Matsumoto, M., Terada, S. and Tsuboi, T.(2023)Distinct lactate metabolism between hepatocytes and myotubes revealed by live cell imaging with genetically encoded indicators.Biochem Biophys Res Commun.,DOI:10.1016/j.bbrc.2023.149416. Nguyen, K.-O.T., Do, T.-N, Dang, K.-P., Sato, M. and Hirai, M.Y.(2023)Single-grain-based widely targeted metabolomics profiling of sixty-four accessions of Japanese wild soybean (Glycin soja Sieb. Et Zucc.). IFST.,DOI:10.1111/ijfs.16654. Tsuno, S., Harada, K., Horikoshi.M., Mita, M., Kitaguchi, T., Hirai, M.Y., Matsumoto, M. and Tsuboi, T.(2023) Mitochondrial ATP concentration decreases immediately after glucose administration to glucose-deprived hepatocytes. FEBS Open Bio.,DOI:10.1002/2211-5463.13744. Kawade, K., Tabeta, H., Ferjani, A. and Hirai, M.Y.(2023) The Roles of Functional Amino Acids in Plant Growth and Development. Plant Cell Physiol.,DOI:10.1093/pcp/pcad071. Uchida, K., Kim, J.S., Sato, M., Tabeta, H., Mochida, K. and Hirai, M.Y.(2023) A metabolome genome-wide association study implicates histidine N-pi-methyltransferase as a key enzyme in N-methylhistidine biosynthesis in Arabidopsis thaliana. Front. Plant Sci.,DOI:10.3389/fpls.2023.1201129. Fuji, Y., Uchida, K., Akashi, T., Ohtsuki, T., Matsufuji, H. and Hirai, M.Y.(2023) Molecular Identification of UDP-Sugar Dependent Glycosyltransferase and Acyltransferase Involved in the Phenylethanoid Glycoside Biosynthesis Induced by Methyl Jasmonate in Sesamum indicum L. Plant Cell Physiol.,DOI:10.1093/pcp/pcad053. Miyamoto, H., Shigeta, K., Suda, W., Ichihashi, Y., Nihei, N., Matsuura, M., Tsuboi, A., Tominaga, N., Aono, M., Sato, M., Taguchi, S., Nakaguma, T., Tsuji, N., Ishii, C., Matsushita, T., Shindo, C., Ito, T., Kato, T., Kurotani, A., Shima, H., Moriya, S., Wada, S., Horiuchi, S., Satoh, T., Mori, K., Nishiuchi, T., Miyamoto, H., Kodama, H., Hattori, M., Ohno, H., Kikuchi, K. and Hirai, M.Y.(2023) An agroecological structure model of compost—soil—plant interactions for sustainable organic farming. ISME Commun,DOI:10.1038/s43705-023-00233-9. Uchida, K. and Hirai, M.Y.(2023) A simple method for creating transgenic pea hairy roots using a Japanese pea cultivar and a Japanese Rhizobium radiobacter strain. Plant Biotechnol., DOI:10.5511/plantbiotechnology.22.1219c Tojo, H., Tabeta, H., Gunji, S., Hirai, M.Y., David, P., Javot, H. and Ferjani, A.(2023) Roles of type II H+-PPases and PPsPase1/PECP2 in early developmental stages and PPi homeostasis of Arabidopsis thalianaFront. Plant Sci., 14:1031426., DOI:10.3389/fpls.2023.1031426 Tabeta, H., Gunji, S., Kawade, K. and Ferjani, A.(2023) Leaf-size control beyond transcription factors: Compensatory mechanismsFront. Plant Sci., 13:1024945., DOI:10.3389/fpls.2022.1024945 Toyooka, K., Goto,Y., Hashimoto, K., Wakazaki, M., Sato, M. and Hirai, M.Y.(2023) Endoplasmic Reticulum Bodies in the Lateral Root Cap are Involved in the Direct Transport of Beta-Glucosidase to Vacuoles. Plant and Cell Physiology, pcac177, DOI:10.1093/pcp/pcac177その他の発行物
アグリバイオ 2023年4月号 vol.7 No.4連載「農作物のホロゲノム育種」第3回
「ホロゲノムの重要因子を探索する解析技術」
藤佑志郎、成川恵、平井優美、市橋泰範